Speaker
Charly Empereur-mot
(University of Applied Sciences of Southern Switzerland (SUPSI))
Description
European project MIMIC-KeY (www.mimickey.eu) aims at creating synthetic extracellular vesicles (EVs) and demonstrating their use with the specific delivery of therapeutic cargo for treating lysosomal bone metabolic disease. Here we present a brief report on computational analyses that assisted the design of artificial nanoparticles consisting of a breakable organosilica core (allowing high payload encapsulation efficiency and controlled release) surrounded by a single-stack lipid bilayer envelope, notably allowing to host proteins.
Primary author
Charly Empereur-mot
(University of Applied Sciences of Southern Switzerland (SUPSI))