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SUMMARY:Engineering a complex plant biosynthetic pathway in the giant duck
 weed
DTSTART;VALUE=DATE-TIME:20260929T100000Z
DTEND;VALUE=DATE-TIME:20260929T101500Z
DTSTAMP;VALUE=DATE-TIME:20260916T130450Z
UID:indico-contribution-2900@cern.ch
DESCRIPTION:Speakers: Meret Huber (University of Mainz)\nDuckweeds are pro
 mising photosynthetic chassis for plant synthetic biology. Yet\, it remain
 s unclear whether they can support the heterologous production of complex 
 specialized metabolites and which expression strategies are best suited fo
 r multigene pathway reconstruction. Here\, I first provide an update on ou
 r transformation protocol for the giant duckweed (*Spirodela polyrhiza*). 
 I then show that a six-gene construct driven by an inducible promoter was 
 the most effective strategy to stably produce the complex anti-diabetic fl
 avonoid glucoside mini-Montbretin A in *S. polyrhiza*. Together\, these re
 sults establish *S. polyrhiza* as a promising chassis to produce complex p
 lant metabolites and highlight the potential of duckweeds for synthetic bi
 ology.\n\nhttps://indico.unina.it/event/117/contributions/2900/
LOCATION:Department of Agricultural Sciences of the University of Napoli F
 ederico II\, Portici\, Italy Sala Cinese
URL:https://indico.unina.it/event/117/contributions/2900/
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