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SUMMARY:Towards a subunit oral vaccine to Newcastle disease in transgenic 
 duckweeds
DTSTART;VALUE=DATE-TIME:20261002T064500Z
DTEND;VALUE=DATE-TIME:20261002T070000Z
DTSTAMP;VALUE=DATE-TIME:20260915T141155Z
UID:indico-contribution-2936@cern.ch
DESCRIPTION:Speakers: Ron Vunsh (Weizmann Institute for Sciences)\nNewcast
 le virus disease (ND) in poultry is highly contagious. Weak strains cause 
 loss in egg production\, virulent strains kill the birds1. NDV virions pos
 ses an envelop and contain a single molecule of linear\, negative sense RN
 A coding for at least six proteins. The important proteins for subunit vac
 cines are two glycoproteins: the hemagglutinin-neuraminidase (HN)\, and th
 e fusion protein (F)\, which are used as antigens for immunization. Immuni
 zation is currently by injection\, nasal spray\, ocular or drinking water 
 that contain the HN antigen. \n\nDuckweeds are small\, edible monocot plan
 ts that float on the surface of fresh water and need only light\, air and 
 some common minerals for rapid growth. Plants of these genera are preferre
 d food as indicated by their name. Transgenic edible plants can deliver va
 ccines to different animals2.\n\nWe introduced HN and the F protein genes 
 into a duckweed species to deliver these antigens for induction of protect
 ive immune response in chickens. We get high expression of both antigens i
 n the transgenic plants\, which grow normally with no apparent phenotypic 
 change.\n\nhttps://indico.unina.it/event/117/contributions/2936/
LOCATION:Department of Agricultural Sciences of the University of Napoli F
 ederico II\, Portici\, Italy Sala Cinese
URL:https://indico.unina.it/event/117/contributions/2936/
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