Francesco Paolo Casale
(Helmholtz Munich)
20/12/23, 10:20
Human genetics provides a robust avenue for causal inference, avoiding the pitfalls of reverse causation thanks to the stable nature of the genome. Specifically, Mendelian randomization (MR) can leverage genetic information to assess causal relationships between risk factors and disease outcomes. For example, through MR, researchers have confirmed the detrimental impact of LDL cholesterol in...