We investigate a large set of electronic health records (EHRs) collected by wellbeing services county of Soutwest Finland (Varha) [1]. Different diseases have different prevalence in a given population. For this reason, the observation of a specific comorbidity in a given patient could be just the result of a random co-occurrence of two unrelated diseases. Therefore a comorbidity net- work of...
I will recap our effort to represent populations of cells using Maximum-Entropy models defined on the space of single-cell metabolic states. At odds with more conventional optimization-based theories, these models place the emphasis on (a) cell-to-cell variability, (b) its relationship with fitness, and (c) inter-cellular interactions. Advantages, limitations and challenges will hopefully...
Stochastic resonance (SR) phenomena provide insight into the behavior of complex biological sys- tems. Furthermore, a method for characterizing SR-type behavior in excitable systems with ape- riodic and arbitrary inputs, such as broadband signals, has been developed and termed aperiodic stochastic resonance (ASR). It was discovered that noise can enhance the response of a sensory neu- ron to a...
