Eukaryotic cells maintain their internal order through a hectic process of sorting and distillation of molecular factors taking place on their lipid membranes. A similar sorting process is implied in the assembly and budding of enveloped viruses. We have proposed a theoretical model of the process, in which molecular sorting emerges from the coupling of phase separation and membrane bending....
Molecular sorting is a vital process in eukaryotic cells, where proteins and other biomolecules are sorted and encapsulated into lipid vesicles for targeted transport to specific organelles and sub- cellular locations. Recent studies suggest this process is driven by a physical mechanism based on phase separation, in which the formation and growth of sorting domains depends primarily on direct...
